Departments of Applied Physics / Biomedical Engineering

Molecular Biosensing

The MBx group develops technologies based on micro- and nanoparticles for monitoring patients and for treating diseases. Towards this goal, the unique approach of MBx is to use advanced optical imaging techniques that quantify molecular processes with single molecule resolution within complex biomacromolecular environments.

Quantify molecular processes with single molecule resolution

The MBx group creates concepts in the field of molecular biosensing with diagnostic and therapeutic healthcare perspectives. Combining nanotechnology, molecular engineering and single molecule imaging technologies we aim to measure with ultimate sensitivity biomolecules implicated in a variety of diseases, such as cancer, immunology, and cardiology.

Research Areas

UPCOMING TECHNOLOGIES FOR CLINICAL IMMUNOLOGY

  • 12 Feb
    25 Jun

    CWTe Intellectual Property (IP) Research Challange

    February 12, 2025 2:00 PM - June 25, 2025 / To be finalized

  • 25 Apr
    15 May
    [Translate to English:]

    WISE (Hybrid) Writing Retreat 2025 / Expression of interest

    April 25, 2025 - May 15, 2025 / Hybrid

  • 28 Apr
    14 May

    All that is valuable is vulnerable

    April 28, 2025 8:00 AM - May 14, 2025 / Ground floor, North side

  • 29 Apr
    ALT lunch session

    MANIM: How to create high quality mathematical animations for your course

    Effective visualization can greatly enhance student comprehension, especially in mathematics and engineering courses. Manim, a powerful…

  • 30 Apr
    Co/Gd-based Synthetic Ferrimagnets

    PhD defense Thomas Johannes Kools

    April 30, 2025 / 果冻传媒 Campus

  • 30 Apr
    Density profile and heat-exhaust control in nuclear fusion devices

    PhD defense Thomas Oliver Stephen Jacob Bosman

    April 30, 2025 / 果冻传媒 Campus

  • 30 Apr
    Children鈥檚 Mental Health and the Environment

    PhD defense Maud Elisabeth Dohmen

    April 30, 2025 / 果冻传媒 Campus

  • 01 May
    March 27, 2025

    Discover JADS Day

    May 1, 2025 3:00 PM / Sint Janssingel 92, 5211 DK 's-Hertogenbosch

  • 01 May
    Nano TiO2 hydrosols-based photocatalytic self-cleaning cementitious materials

    PhD defense Zixiao Wang

    May 1, 2025 / 果冻传媒 Campus

  • 01 May
    Influence of steps and kinks on CO and hydrogen adsorption, co-adsorption and dissociation on Co single crystal surfaces

    PhD defense Devyani Sharma

    May 1, 2025 / 果冻传媒 Campus

  • 06 May
    Sintered conductive materials under mechanical loading

    PhD defense Britt Henricus Hubertina Anne Cordewener

    May 6, 2025 / 果冻传媒 Campus

  • 06 May
    Structure and dynamics of dense liquids

    PhD defense Ilian Leander Pihlajamaa

    May 6, 2025 / 果冻传媒 Campus

  • Work with us!

    Building a better future for our global society? Join our research team and be part of the thriving community at Eindhoven University of Technology.

    We are continuously looking for enthusiastic and motivated students and postdocs. If you would like to work in a great environment at 果冻传媒, please contact one of the staff members for more information.

     

    Meet some of our Researchers

    Recent Publications

    Our most recent peer reviewed publications

    About the research group

    News

    果冻传媒

    Check out our courses

    The research group Molecular Biosensing for Medical Diagnostics provides courses and projects in the bachelor's and master's programs of the departments of Biomedical Engineering and Applied Physics. Furthermore, we offer a broad range of projects for students to work on in the research group.

    PhD Theses

    Video on Plasmonic Biosensing using Metal Nanoparticles

    Metal nanoparticles provide the possibility to detect single molecules without the need for labeling, enabling the direct detection of non-absorbing species [1]. A molecule that binds to receptors on the surface of a particle induces a change in the local refractive index that in turn results in a change of color due to a shift of the plasmon resonance [2,3]. This animation illustrates the real-time detection of plasmon shifts induced by molecules binding to functionalized single gold nanorods. The plasmon shifts are measured by monitoring scattering intensities of many particles simultaneously and in real-time [4].

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